Fungicidal mixtures based on benzamidoxime derivative and a strobilurin derivative

ABSTRACT

The invention relates to a fungicidal mixture containing (1) a benzamidoxime derivative of formula (I), whereby the substituent and the index are defined as follows: R represents hydrogen, halogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4  alkoxy or C 1 -C 4  haloalkoxy, n represents 1, 2 or 3; and at least one additional strobilurin derivative, selected from (2) a trifloxystrobin of formula (II), or (3) a picoxystrobin of formula (III), or (4) a pyraclostrobin of formula (IV), or (5) a strobilurin derivative of formula (V), or (6) a strobilurin derivative of formula (VI), or (7) a dimoxystrobin of formula (VII), or (8) a kresoxim methyl of formula (VIII), or (9) an azoxystrobin of formula (IX), or (10) a strobilurin derivative of formula (X) in a synergistically active quantity.

The present invention relates to fungicidal mixtures, comprising

(1) a benzamidoxime derivative of the formula I

where the substituent and the index may be as defined below:

-   -   R is hydrogen, halogen, C₁-C₄-alkyl, C₁-C₄-haloalkyl,        C₁-C₄-alkoxy or C₁-C₄-haloalkoxy    -   n 1, 2 or 3,        and at least one strobilurin derivative, selected from

(2) trifloxystrobin of the formula II

(3) picoxystrobin of the formula III

or

(4) pyraclostrobin of the formula IV

(5) a strobilurin derivative of the formula V

(6) a strobilurin derivative of the formula VI

(7) dimoxystrobin of the formula VII

(8) kresoxim-methyl of the formula VIII

(9) azoxystrobin of the formula IX

(10) a strobilurin derivative of the formula X

in a synergistically effective amount.

Moreover, the invention relates to a method for controlling harmfulfungi using mixtures of the compounds I and at least one of thecompounds II to X, to the use of the compound I and at least one of thecompounds II to X for preparing such mixtures and to compositionscomprising these mixtures.

The compounds of the formula I have already been disclosed in EP-A-1 017670.

EP-A-1 017 670 discloses a number of active compound combinations ofcompounds of the formula I and a large number of other fungicidalcompounds.

Trifloxystrobin of the formula II and its use as crop protection agentare described in EP-A-0 460 575.

Picoxystrobin is disclosed in EP-A-0 326 330.

Pyraclostrobin of the formula IV, too, has already been disclosed and isdescribed in EP-A-0 804 421.

The strobilurin derivative of the formula V is disclosed in DE-A-196 02095.

The strobilurin derivative of the formula VI, too, has been disclosedand is described in EP-A-0 876 332.

Dimoxystrobin of the formula VII is disclosed in EP-A-0 477 631.

Kresoxim-methyl of the formula VIII is described in EP-A-0 253 213.

Azoxystrobin of the formula IX is described in EP-A-0 382 375.

The strobilurin derivative of the formula X is disclosed in WO 98/21189and WO 01/84931.

It is an object of the present invention to provide mixtures which, withthe total amount of active compounds applied being reduced, haveimproved activity against harmful fungi (synergistic mixtures), with aview to reducing the application rates and improving the activityspectrum of the known compounds I to X.

We have found that this object is achieved by the mixture, defined atthe outset, of a compound of the formula I and at least one strobilurinderivative of the formulae II to X. Moreover, we have found thatsimultaneous, that is joint or separate, application of the compound Iand at least one of the compounds II to X or of the compound I and atleast one of the compounds II to x in succession allows better controlof harmful fungi than is possible with the individual compounds alone.

The benzamidoxime derivative of the formula I

is disclosed in EP-A-1 017 670.

Trifloxystrobin of the formula II

is disclosed in EP-A 0 460 572.

Picoxystrobin of the formula III

is disclosed in EP-A-0 326 330.

Pyraclostrobin of the formula IV

is disclosed in EP-A 0 804 421.

The strobilurin derivative of the formula V

is disclosed in DE-A-196 02 095.

The strobilurin derivative of the formula VI

is disclosed in EP-A-0 876 332.

Dimoxystrobin of the formula VII

is disclosed in EP-A-0 477 631.

Kresoxim-methyl of the formula VIII

is described in EP-A-0 253 213.

Azoxystrobin of the formula IX

The strobilurin derivative of the formula X

is described in EP-A-0 382 375.

In the context of the present invention, halogen is fluorine, chlorine,bromine and iodine and in particular fluorine, chlorine and bromine.

The term “alkyl” embraces straight-chain and branched alkyl groups.These are preferably straight-chain or branched C₁-C₄-alkyl groups.Examples of alkyl groups are alkyl such as, in particular, methyl,ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl and1,1-dimethylethyl.

Haloalkyl is an alkyl group as defined above which is partially or fullyhalogenated by one or more halogen atoms, in particular fluorine andchlorine. Preferably, 1 to 3 halogen atoms are present, and thedifluoromethyl and trifluoromethyl groups are particularly preferred.

What has been said above with respect to the alkyl group and thehaloalkyl group applies correspondingly to the alkyl and haloalkylgroups in alkoxy and haloalkoxy.

Owing to the basic character of their nitrogen atoms, the compounds I toX are capable of forming salts or adducts with inorganic or organicacids or with metal ions.

Examples of inorganic acids are hydrohalic acids, such as hydrofluoricacid, hydrochloric acid, hydrobromic acid and hydriodic acid, andfurthermore carbonic acid, sulfuric acid, phosphoric acid and nitricacid.

Suitable organic acids are, for example, formic acid, and alkanoicacids, such as acetic acid, trifluoroacetic acid, trichloroacetic acidand propionic acid, and also glycolic acid, thiocyanic acid, lacticacid, succinic acid, citric acid, benzoic acid, cinnamic acid, oxalicacid, alkylsulfonic acids (sulfonic acids having straight-chain orbranched alkyl radicals of 1 to 20 carbon atoms), arylsulfonic acids oraryldisulfonic acids (aromatic radicals, such as phenyl and naphthyl,which carry one or two sulfo groups), alkylphosphonic acids (phosphonicacids having straight-chain or branched alkyl radicals of 1 to 20 carbonatoms), arylphosphonic acids or aryldiphosphonic acids (aromaticradicals, such as phenyl and naphthyl, which carry one or two phosphoricacid radicals), it being possible for the alkyl or aryl radicals tocarry further substituents, e.g. p-toluenesulfonic acid, salicylic acid,p-aminosalicylic acid, 2-phenoxybenzoic acid, 2-acetoxybenzoic acid,etc.

Suitable metal ions are, in particular, the ions of the elements of thesecond main group, in particular calcium and magnesium, of the third andfourth main group, in particular aluminum, tin and lead, and of thefirst to eighth transition group, in particular chromium, manganese,iron, cobalt, nickel, copper, zinc and others. Particular preference isgiven to the metal ions of the elements of the transition groups of thefourth period. The metals can exist in the various valences which theycan assume.

Preference is given to the compound of the formula I in which R ishydrogen.

Examples of compounds of the formula I are listed in Table 1. (I)

No. R n m.p. ° C. I.1 H 1 58-60 I.2 4-F 1 75-77 I.3 4-Cl 1 81-83 I.44-OCH₃ 1 57-59 I.5 4-CF₃ 1

Preference is given to mixtures of a benzamidoxime derivative of theformula I with trifloxystrobin of the formula II.

Preference is also given to mixtures of a benzamidoxime derivative ofthe formula I with picoxystrobin of the formula III.

Preference is given to mixtures of a benzamidoxime derivative of theformula I with pyraclostrobin of the formula IV.

Preference is furthermore also given to mixtures of a benzamidoximederivative of the formula I with a strobilurin derivative of the formulaV.

Preference is furthermore also given to mixtures of a benzamidoximederivative of the formula I with dimoxystrobin of the formula VI.

Preference is furthermore also given to mixtures of a benzamidoximederivative of the formula I with kresoxim-methyl of the formula VII.

Preference is furthermore also given to mixtures of a benzamidoximederivative of the formula I with azoxystrobin of the formula VIII.

Preference is also given to mixtures of a benzamidoxime derivative withthe strobilurin derivative of the formula IX.

Preference is also given to mixtures of a benzamidoxime derivative withthe strobilurin derivative of the formula X.

Preference is also given to three-component mixtures of a benzamidoximederivative of the formula I with two of the abovementioned strobilurinderivatives of the formulae II to X.

When preparing the mixtures, it is preferred to employ the pure activecompounds I to X, to which further active compounds against harmfulfungi or other pests, such as insects, arachnids or nematodes, or elseherbicidal or growth-regulating active compounds or fertilizers can beadded.

The mixtures of the active compound I and at least one of the compoundsII to X, or the compound I and at least one of the compounds II to Xapplied simultaneously, jointly or separately, exhibit outstandingactivity against a wide range of phytopathogenic fungi, in particularfrom the classes of the Ascomycetes, Basidiomycetes, Phycomycetes andDeuteromycetes. Some of them act systemically and can therefore also beemployed as folia- and soil-acting fungicides.

They are especially important for controlling a large number of fungi ina variety of crop plants, such as cotton, vegetable species (for examplecucumbers, beans, tomatoes, potatoes and cucurbits), barley, grass,oats, bananas, coffee, corn, fruit species, rice, rye, soya, grapevine,wheat, ornamentals, sugarcane, and a variety of seeds.

They are particularly suitable for controlling the followingphytopathogenic fungi: Blumeria graminis (powdery mildew) in cereals,Erysiphe cichoracearum and Sphaerotheca fuliginea in cucurbits,Podosphaera leucotricha in apples, Uncinula necator in grapevines,Puccinia species in cereals, Rhizoctonia species in cotton, rice andlawns, Ustilago species in cereals and sugarcane, Venturia inaequalis(scab) in apples, Helminthosporium species in cereals, Septoria nodorumin wheat, Botrytis cinera (gray mold) in strawberries, vegetables,ornamentals and grapevines, Cercospora arachidicola in groundnuts,Pseudocercosporella herpotrichoides in wheat and barley, Pyriculariaoryzae in rice, Phytophthora infestans in potatoes and tomatoes,Plasmopara viticola in grapevines, Pseudoperonospora species in hops andcucumbers, Alternaria species in vegetables and fruit, Mycosphaerellaspecies in bananas and Fusarium and Verticillium species.

The compound I and at least one of the compounds II to X can be appliedsimultaneously, either together or separately, or in succession, thesequence, in the case of separate application, generally not having anyeffect on the result of the control measures.

The compounds I and II are usually applied in a weight ratio of from20:1 to 1:20, in particular from 10:1 to 1:10, preferably from 5:1 to1:5.

The compounds I and III are usually applied in a weight ratio of from20:1 to 1:20, in particular from 10:1 to 1:10, preferably from 5:1 to1:5.

The compounds I and IV are usually applied in a weight ratio of from20:1 to 1:20, in particular from 10:1 to 1:10, preferably from 5:1 to1:5.

The compounds I and V are usually applied in a weight ratio of from 20:1to 1:20, in particular from 10:1 to 1:10, preferably from 5:1 to 1:5.

The compounds I and VI are usually applied in a weight ratio of from20:1 to 1:20, in particular from 10:1 to 1:10, preferably from 5:1 to1:5.

The compounds I and VII are usually applied in a weight ratio of from20:1 to 1::20, in particular from 10:1 to 1:10, preferably from 5:1to1:5.

The compounds I and VIII are usually applied in a weight ratio of from20:1 to 1:20, in particular from 10:1 to 1:10, preferably from 5:1 to1:5.

The compounds I and IX are usually applied in a weight ratio of from20:1 to 1:20, in particular from 10:1 to 1:10, preferably from 5:1 to1:5.

The compounds I and X are usually applied in a weight ratio of from 20:1to 1:20, in particular from 10:1 to 1:10, preferably from 5:1 to 1:5.

Depending on the kind of effect desired, the application rates of themixtures according to the invention are, in particular in agriculturalcrop areas, from 0.01 to 8 kg/ha, preferably from 0.1 to 5 kg/ha, inparticular from 0.1 to 3.0 kg/ha.

The application rates of the compound I are from 0.01 to 1 kg/ha,preferably from 0.05 to 0.5 kg/ha, in particular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound II, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound III, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound IV, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound V, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound VI, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound VII, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound VIII, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound IX, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

Correspondingly, in the case of the compound X, the application ratesare from 0.01 to 1 kg/ha, preferably from 0.02 to 0.5 kg/ha, inparticular from 0.05 to 0.3 kg/ha.

For seed treatment, the application rates of the mixture are generallyfrom 0.001 to 250 g/kg of seed, preferably from 0.01 to 100 g/kg, inparticular from 0.01 to 50 g/kg.

If pathogenic harmful fungi are to be controlled, the separate or jointapplication of the compound I and at least one of the compounds II to Xor of the mixtures of the compound I and at least one of the compoundsII to X is effected by spraying or dusting the seeds, the plants or thesoils before or after sowing of the plants, or before or after plantemergence.

The fungicidal synergistic mixtures according to the invention, or thecompound I and at least one of the compounds II to X, can be formulatedfor example in the form of ready-to-spray solutions, powders andsuspensions or in the form of highly concentrated aqueous, oily or othersuspensions, dispersions, emulsions, oil dispersions, pastes, dusts,materials for broadcasting or granules, and applied by spraying,atomizing, dusting, broadcasting or watering. The use form depends onthe intended purpose; in any case, it should ensure as fine and uniformas possible a distribution of the mixture according to the invention.

The formulations are prepared in a known manner, e.g. by extending theactive compound with solvents and/or carriers, usually using inertadditives such as emulsifiers and dispersants.

Suitable surfactants are the alkali metal salts, alkaline earth metalsalts and ammonium salts of aromatic sulfonic acids, e.g. ligno-,phenol-, naphthalene- and dibutylnaphthalenesulfonic acid, and of fattyacids, alkyl- and alkylarylsulfonates, alkyl, lauryl ether and fattyalcohol sulfates, and salts of sulfated hexa-, hepta- and octadecanols,or of fatty alcohol glycol ethers, condensates of sulfonated naphthaleneand its derivatives with formaldehyde, condensates of naphthalene or ofthe naphthalenesulfonic acids with phenol and formaldehyde,polyoxyethylene octylphenol ether, ethoxylated isooctyl-, octyl-ornonylphenol, alkylphenol polyglycol ethers, tributylphenyl polyglycolethers, alkylaryl polyether alcohols, isotridecyl alcohol, fattyalcohol/ethylene oxide condensates, ethoxylated castor oil,polyoxyethylene alkyl ethers or polyoxypropylene alkyl ethers, laurylalcohol polyglycol ether acetate, sorbitol esters, lignosulfite wasteliquors or methylcellulose.

Powders, materials for broadcasting and dusts can be prepared by mixingor jointly grinding the compound I and at least one of the compounds IIto X, or the mixture of the compounds I and at least one of thecompounds II to X, with a solid carrier.

Granules (e.g. coated granules, impregnated granules or homogeneousgranules) are usually prepared by binding the active compound, or activecompounds, to a solid carrier.

Fillers or solid carriers are, for example, mineral earths, such assilicas, silica gels, silicates, talc, kaolin, limestone, lime, chalk,bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate,magnesium sulfate, magnesium oxide, ground synthetic materials andfertilizers, such as ammonium sulfate, ammonium phosphate, ammoniumnitrate, ureas, and products of vegetable origin, such as cereal meal,tree bark meal, wood meal and nutshell meal, cellulose powders or othersolid carriers.

The formulations generally comprise from 0.1 to 95% by weight,preferably 0.5 to 90% by weight, of the compound I and at least one ofthe compounds II to X or of the mixture of the compound I and at leastone of the compounds II to X. The active compounds are employed in apurity of from 90% to 100%, preferably 95% to 100% (according to NMRspectrum or HPLC).

The compound I and at least one of the compounds II to X, the mixtures,or the corresponding formulations, are applied by treating the harmfulfungi, their habitat, or the plants, seeds, soils, areas, materials orspaces to be kept free from them with a fungicidally effective amount ofthe mixture, or of the compound I and at least one of the compounds IIto X in the case of separate application.

Application can be effected before or after infection by the harmfulfungi.

USE EXAMPLE

The synergistic activity of the mixtures according to the invention wasdemonstrated by the following experiments:

The active compounds, separately or together, were formulated as a 10%emulsion in a mixture of 63% by weight of cyclohexanone and 27% byweight of emulsifier, and diluted with water to the desiredconcentration.

Evaluation was carried out by determining the infected leaf areas inpercent. These percentages were converted into efficacies. The efficacy(w) was calculated as follows using Abbot's formula:$W = {\left( {1 - \frac{\alpha}{\beta}} \right) \cdot 100}$

-   -   α corresponds to the fungal infection of the treated plants in %        and    -   β corresponds to the fungal infection of the untreated (control)        plants in %

An efficacy of 0 means that the infection level of the treated plantscorresponds to that of the untreated control plants; an efficacy of 100means that the treated plants were not infected.

The expected efficacies of the mixtures of the active compounds weredetermined using Colby's formula [R. S. Colby, Weeds 15, 20-22 (1967)]and compared with the observed efficacies.E =x+y−x·y/100  Colby's formula:

-   -   E expected efficacy, expressed in % of the untreated control,        when using the mixture of the active compounds A and B at the        concentrations a and b    -   x efficacy, expressed in % of the untreated control, when using        active compound A at a concentration of a    -   y efficacy, expressed in % of the untreated control, when using        active compound B at a concentration of b

Use Example 1 Activity Against Mildew of Wheat Caused by Erysiphe [syn.Blumeria] graminis forma Specialis. tritici

Leaves of wheat seedlings of the cultivar “Kanzler” grown in pots weresprayed to runoff point with an aqueous preparation of active compoundwhich had been prepared from a stock solution comprising 10% of activecompound, 85% of cyclohexanone and 5% of emulsifier. 24 hours after thespray coating had dried on, the plants were dusted with spores of mildewof wheat (Erysiphe [syn. Blumeria] graminis forma specialis. tritici).The test plants were then placed in a greenhouse at 20-24° C. and 60-90%relative atmospheric humidity. After 7 days, the extent of the mildewdevelopment was determined visually in % infection of the entire leafarea.

The visually determined values for the percentage of infected leaf areaswere converted into efficacies in % of the untreated control. Anefficacy of 0 means the same degree of infection as in the untreatedcontrol, an efficacy of 100 means 0% infection. The expected efficaciesfor combinations of active compounds were determined using Colby'sformula (Colby, S. R. (Calculating synergistic and antagonisticresponses of herbicide Combinations”, Weeds, 15, p. 20-22, 1967) andcompared to the observed effacacies. TABLE 2 Concentration of activeEfficacy in % compound in the spray of the untreated Active compoundliquor in ppm control Control (94% infection) 0 (untreated) Compound I =I.1 1 47 0.25 36 0.06 5 Compound IV = pyraclostrobin 1 0 0.25 0 0.06 0Compound VIII = kresoxim- 1 0 methyl 0.25 0 0.06 0 Compound IX =azoxystrobin 1 0 0.25 0 0.015 0

TABLE 3 Observed Calculated Combinations claimed efficacy efficacy*)Compound I = I.1 + Compound 36 5 IV = pyraclostrobin 0.06 + 1 ppmmixture 1:16 Compound I = I.1 + Compound 25 5 IV = pyraclostrobin 0.06 +0.25 ppm mixture 1:4 Compound I = I.1 + Compound 79 47 IV =pyraclostrobin 1 + 0.25 ppm mixture 4:1 Compound I = I.1 + Compound 6847 IV = pyraclostrobin 1 + 0.06 ppm mixture 16:1 Compound I = I.1 +Compound 25 5 VIII = kresoxim-methyl 0.06 + 1 ppm mixture 1:16 CompoundI = I.1 + Compound 25 5 VIII = kresoxim-methyl 0.06 + 0.25 ppm mixture1:4 Compound I = I.1 + Compound 68 47 VIII = kresoxim-methyl 1 + 0.25ppm mixture 4:1 Compound I = I.1 + Compound 68 47 VIII = kresoxim-methyl1 + 0.06 ppm mixture 16:1 Compound I = I.1 + Compound 36 5 IX =azoxystrobin 0.06 + 1 ppm mixture 1:16 Compound I = I.1 + Compound 25 5IX = azoxystrobin 0.06 + 0.25 ppm mixture 1:4 Compound I = I.1 +Compound 36 5 IX = azoxystrobin 0.06 + 0.015 ppm mixture 4:1 Compound I= I.1 + Compound 47 36 IX = azoxystrobin 0.25 + 0.015 ppm mixture 16:1*)efficacy calculated using Colby's formula

The test results show that in all mixing ratios the observed efficacy ishigher than the efficacy calculated beforehand using Colby's formula(from Synerg 178. XLS).

1. A fungicidal mixture, comprising (1) a benzamidoxime derivative ofthe formula I

where the substituent and the index may be as defined below: R ishydrogen, halogen, C₁-C₄-alkyl, C₁-C₄-haloalkyl, C₁-C₄-alkoxy orC₁-C₄-haloalkoxy n 1,2or 3, and at least one strobilurin derivative,selected from (2) trifloxystrobin of the formula II

(3) picoxystrobin of the formula III

(4) pyraclostrobin of the formula IV

(5) a strobilurin derivative of the formula V

(6) a strobilurin derivative of the formula VI

(7) dimoxystrobin of the formula VII

(8) kresoxim-methyl of the formula VIII

(9) azoxystrobin of the formula IX

(10) a strobilurin derivative of the formula X

in a synergistically effective amount.
 2. A fungicidal mixture asclaimed in claim 1 where in the formula I the radical R is hydrogen. 3.A fungicidal mixture as claimed in claim 1, comprising a compound of theformula I and trifloxystrobin of the formula II.
 4. A fungicidal mixtureas claimed in claim 1, comprising a compound of the formula I andpicoxystrobin of the formula III.
 5. A fungicidal mixture as claimed inclaim 1, comprising a compound of the formula I and pyraclostrobin ofthe formula IV.
 6. A fungicidal mixture as claimed in claim 1,comprising a compound of the formula I and dimoxystrobin of the formulaVII.
 7. A fungicidal mixture as claimed in claim 1, comprising acompound of the formula I and kresoxim-methyl of the formula VII.
 8. Afungicidal mixture as claimed in claim 1, comprising a compound of theformula I and strobilurin derivative of the formula VI.
 9. A fungicidalmixture as claimed in claim 1, comprising a compound of the formula Iand azoxystrobin of the formula IX.
 10. A fungicidal mixture as claimedin claim 1, comprising a compound of the formula I and strobilurinderivative of the formula X.
 11. A fungicidal mixture as claimed inclaim 1, wherein the weight ratio of the compound of the formula I tothe respective strobilurin derivative of the formula II to X is from20:1 to 1:20.
 12. A method for controlling harmful fungi, whichcomprises treating the harmful fungi, their habitat or the plants,seeds, soils, areas, materials or spaces to be kept free from them withthe fungicidal mixture as claimed in claim
 1. 13. A method as claimed inclaim 12, wherein the compound of the formula I and at least onecompound of the formula II to X are applied simultaneously, that istogether or separately, or in succession.
 14. A method as claimed inclaim 12, wherein the fungicidal mixture or the compound of the formulaI and at least one compound of the formulae II to X is/are applied in anamount of from 0.01 to 8 kg/ha.
 15. A fungicidal composition, comprisingthe fungicidal mixture as claimed in claim 1 and a solid or liquidcarrier.